Introduction: A New Era of Safer, Smarter IVF
The world of IVF is always changing and one of the most exciting medical breakthroughs in fertility care today is embryo genetic testing. Whether you are planning or undergoing IVF, understanding the role of genetics in conception and healthy pregnancy is a game-changer.
At The Bliss Care, we believe that knowledge is power when it comes to couples. That’s why our team of fertility experts helps you explore the latest technologies like preimplantation genetic diagnosis in Greater Noida so that you can make informed decisions about your fertility journey.
Let’s explain what PGD and PGS mean, the difference between them, and how they are so important for your IVF success.
What is Genetic Testing in IVF?
Before the embryo is transferred to the uterus, fertility specialists can now test the genetic make-up of the embryo. This is used to select only healthy embryos (i.e., not having specific genetic or chromosomal abnormalities) for implantation.
This early screening will not only increase the success of the IVF procedure but also will decrease the risk of miscarriages and genetic disorders in the baby.
There are two major categories of tests:
- PGD (Preimplantation genetic diagnosis)
- PGS (Preimplantation Genetic Screening)
Both are performed before the embryo transfer; however their purpose is a little different.
What is PGD (Preimplantation Genetic Diagnosis)?
Preimplantation Genetic Diagnosis (PGD) is used for either or both parents that are known to be carriers of a genetic disorder. It helps to identify the embryos that may be affected with that particular inherited problem.
For example, if one of the parents carries a disease like cystic fibrosis, thalassemia or muscular dystrophy, PGD can establish whether the embryo has inherited the same gene mutation.
What is PGS (Preimplantation Genetic Screening)?
Preimplantation Genetic Screening (PGS), currently often referred to as PGT-A (Preimplantation Genetic Testing for Aneuploidies) is used to screen embryos for abnormal numbers of chromosomes.
Chromosomes contain our genetic information and an extra or missing chromosome can lead to disorders such as Down Syndrome, Turner Syndrome or miscarriage.
PGS is required for couples facing:
- Repeated IVF failures
- Recurrent miscarriages
- Advanced maternal age (35+)
- Poor embryo quality
This screening does increase the chances of transfer of chromosomally normal embryos, and thus increases the chances of a healthy, successful pregnancy.
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PGD vs PGS: The Key Differences
| Aspect | PGD (Preimplantation Genetic Diagnosis) | PGS (Preimplantation Genetic Screening) |
| Purpose | Detects specific inherited genetic diseases | Detects chromosomal abnormalities |
| When Recommended | If parents are carriers of genetic conditions | For couples with repeated IVF failures, miscarriages, or older age |
| Focus | Disease-specific | Chromosome number and structure |
| Outcome | Prevents inherited diseases | Improves IVF success rate and reduces miscarriage risk |
How the Process Works
How genetic testing fits into your IVF journey at The Bliss Care:
Step 1: Ovarian Stimulation and Egg Retrieval
As we have seen, the IVF process begins by stimulating the ovaries to produce multiple eggs. These eggs are then removed and fertilised with the sperm in our state of the art laboratory.
Step 2: Embryo Development
After fertilisation, the embryos are then cultured for 5-6 days until they are in the blastocyst stage.
Step 3: Embryo Biopsy
A few cells are carefully extracted from each of the embryos for genetic testing. This step is done with extreme precision under a microscope so as not to damage the embryo.
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Step 4: Genetic Testing
The biopsied cells are sent for preimplantation genetic diagnosis in Greater Noida or screening. Advanced genetic tools are then used to analyse the DNA to identify abnormalities.
Step 5: Embryo Transfer
The genetically healthy embryos are only selected and transferred into the uterus with the best chance of a healthy pregnancy.
Conclusion: Building Healthier Families with Science and Care
Genetic testing has transformed IVF into a more accurate, reliable, and human process. By being able to identify healthy embryos before transferring them to the woman, couples can not only increase their chances of getting pregnant, but also ensure that they will have a healthy baby.
If you’re exploring preimplantation genetic diagnosis in Greater Noida, visit The Bliss Care — where science meets sensitivity. Our specialists combine world-class expertise with compassionate care to make your IVF experience safer, more innovative, and more successful.
Because when it comes to the creation of life, every detail and every gene matters.